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4 * Both of these sexual problems are accompanied by clinically significant personal distress manifested by a sense of frustration, grief, incompetence, loss, sadness, sorrow, or worry

The main point is that as one increments diet protein the protein provokes an acid load via the oxidation of sulfur from methionine and cystine, and thence a change in net acid excretion (NAE)

Figure 5: Changes in the body weight and body length of both male and female KID, KIR, and control mice