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Deficiency impairs synthesis of niacin Increased intake reduces utilization of omega-6 fatty (evening primrose oil, acids GLA) Reduces peroxidation of EFAs Increased intake reduces utilization of omega-3 fatty Vitamin E acids Reduces peroxidation of EFAs Omega-3 fatty acids Omega-6 fatty acids Deficiency increases urinary excretion Important in activation of riboflavin (fish oils, EPA, DHA) Deficiency impairs selenium utilization

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