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Fourth, MR requires stringent assumptions, i.e., the genetic variants are associated with the exposure, no confounders of the associations of the genetic variants with the outcomes exist, and the genetic variants are not associated with the outcomes other than via affecting the relevant exposure (no pleiotropy) [17]

To this end, metabolomics has become a valuable scientific tool in deciphering differential metabolic patterns and the factors that drive them

Increasing disease severity was also found in one study to be associated with decreasing relative abundance of Lactobacillus spp

Aquaculture 464, 222228

So far, the possible association between GSTT1 genotype and ASD was investigated only in one study in which no association between individual GSTT1 genotype and risk of ASD development was observed 17 and our results are in agreement with this finding