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Future research should focus on optimizing imaging protocols, validating biomarkers across large patient cohorts, and integrating imaging data with molecular classification systems to enhance precision oncology approaches in GBM treatment

Glutamine metabolism is critical in neutrophils, and GSH serves as a major antioxidant, levels of which are closely related to cellular oxidative state and ROS production

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Notably, some nanomaterials can themselves activate NLRP3 in the CNS [198], underscoring the need for careful nanoengineering and mechanistic evaluation

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