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Iron supply primarily depends on dietary intake ( 2+ , while transferrin in portal blood only binds Fe 3+ ), leading to its degradation in enterocytes and macrophages, resulting in intracellular iron retention and reduced circulating iron levels

GPx6 is a tetramer containing selenocysteine in the active center (Brigelius-Floh and Floh 2020)

NAD+ helps maintain brain health by supporting mitochondrial function in brain cells and protecting against neurodegenerative diseases

The fact that FONE70 alone has induced an excessive amount of ROS in cells and possessed potent cellular destructive power indicates the involvement of endogenous catalase

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