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Strikingly, treatment with a lower dose of methazolamide (daily dose of 200 mg) also resulted in notable improvements in AMS symptoms, particularly headache, irritability, feeling unwell and loss of concentration

AMPH Can Regulate Excitatory as Well as Catecholaminergic Signaling in LC Neurons We previously showed that regulation of the trafficking of a glutamate EAAT3 plays a critical role in regulating glutamatergic inputs into these cells

However, there is substantial debate about whether immobility truly reflects a depressive state or rather an adaptive coping strategy such as energy conservation [21, 22]

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Heparan sulfate signaling in cancer