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[,,] Mechanistically, continuous lipolysis during FGF21 treatment in the adipose tissue enabled the liver to be flooded with fat-derived FFAs, which might cause hepatic steatosis

This blockage in GSL production could be overcome by the overproduction of PAPS, but not of SOTs, substantiating the importance of activated sulfate and co-regulation of sulfate assimilation with GSL production in the cell ( It therefore has been concluded that there must be a plastidial PAPS transporter to enable PAPS to be delivered to the cytoplasm-localized SOT enzymes

Tavor et al., Correlation between CXCR4 and homing or engraftment of acute myelogenous leukemia

184,185,186 The role of the SASP in tumors can be summarized as follows: (1) It promotes the growth and proliferation of tumor cells

During EMT, IL-17 stimulates the phosphorylation of SMAD 2/3 and Erk1/2 in SGECs (53)