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Report on three cases, one of them with late onset during vitamin B12 treatment

The Standards of Medical Care in Diabetes, updated annually, includes dedicated sections on incretin-based therapies relevant for understanding tirzepatide pharmacology and clinical application

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Other Risk Factors : People with chronic alcoholism, those taking certain medications (like metformin or proton pump inhibitors), or individuals with specific genetic mutations affecting B12 metabolism may also benefit from B12 injections

They also considered the question of whether acid-suppressing drugs such as omeprazole or esomeprazole affect vitamin B12 levels ( American Journal of Clinical Nutrition , June 16, 2021}