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Abstract Ferroptosis is a novel regulated cell death characterized by excessive membrane lipid peroxidation in an iron- and ROS-dependent manner, which is increasingly recognized for its role in tumor suppression and overcoming therapy resistance in various cancers

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We found that EBV infection leads to upregulation of p62, which in turn activates NRF2 via the p62-Keap1-NRF2 axis in NPC cells