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10.22203/ecm.v018a03 176 McAfeeP

The SURMOUNT-1 clinical trial tracked weight loss outcomes across all three maintenance dose tiers over 72 weeks in adults with obesity or overweight

However, in human research, whether it is pharmacological or neuroimaging, it is not possible to specifically delineate the pathways, hence, here, we collapse the second and the third pathways, referring to them as the mesocorticolimbic pathway