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The idea is to inject as close to the target tissue as possible

In Handbook of Uncertainty Quantification (eds Ghanem, R., Higdon, D

However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]