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Pharmacological Effects of Natural Medicines for the Management of Epilepsy Despite the increasing number of researches on natural medicine, the ingredients of natural medicine remain complex, such as alkaloids, flavonoids, saccharides, glycosides, quinones, coumarins, lignans, terpenes, volatile oils, saponins, and cardiac glycosides ( 2+ , K + , and Na + ), immune system (i.e., CD3, CD4, IgG, IgA, TNF-, IL-1, IL-2, IL-4, IL-6, and IL-10), glial cells (i.e., lial cell proliferation and potassium uptake ability) and mitochondrial dysfunction and oxidative stress (i.e., oxidation markers, accumulation of Ca 2+ , cell death, and apoptosis)

Deutsch SI, Rosse RB, Schwartz BL, Mastropaolo J

10.1016/j.jpedsurg.2019.10.027 76

Foxp3 + Tregs maintain immune homeostasis in the intestine, and any defects therein are linked to IBD

Asthir B, Kaur S, Mann SK (2009) Effect of salicylic and abscisic acid administered through detached tillers on antioxidant system in developing wheat grains under heat stress