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Plasma lipids are also considered important risk factors and the GLP-1RAs appear to reduce postprandial triglycerides (again by an unknown mechanism), and apolipoprotein (Apo) B48 may be reduced in parallel, suggesting that fat absorption is reduced

Curr Rheumatol Rep

The key difference is that retatrutide provides triple agonism (GLP-1 + GIP + glucagon) while semaglutide provides only GLP-1 agonism

If you say they cost us $7 billion and we spent 3 billion to bring this drug to market, and they're importing products from China and there's no safety nets and nobody's inspecting them, and this is what we're worried about

K.El KhouryJ