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Quantitative and targeted proteomics-based identification and validation of drug efficacy biomarkers

It's a domino effect that starts like this: The hypothalamus in the brain signals the pituitary glands, which then stimulate the adrenal glands to produce the stress hormones

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Melatonin has a pivotal role in the activation of the antioxidant system and induces changes in gene expression of several physiological mechanisms 21,29