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Vitiligo is classified according to its extent and distribution into segmental (affecting one side of the body) and non-segmental (affecting both sides of the body)

Smad, mothers against decapentaplegic homolog

Compared to placebo, patients receiving monthly IV infusions of sifalimumab (1,200, 600, and 200 mg groups) had statistically superior SRI-4 response index compared to placebo that received standard of care treatment at 52 weeks (sifalimumab: 59.8, 56.5, and 58.3 vs

Useful soft tissue endpoints include: muscle fibre organisation vascular response inflammatory marker panels collagen deposition fibroblast activity oxidative stress markers histology scoring cell migration These research areas overlap with tendon and ligament studies but focus more broadly on tissue integrity and repair-associated signalling

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