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Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven

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Prediction and Design of Protease Enzyme Specificity Using a Structure-Aware Graph Convolutional Network

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This result is improved glucose clearance from the blood, which supports energy metabolism and reduces fat storage [6]