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GST Tag Interference with Protein Function Challenge : In some cases, the GST tag can interfere with the function of the target protein, particularly if the protein's active site or interaction domains are close to the fusion point

Inflamm Res 62(4):425440

Psoriasis has been associated with keratinocyte production of LL-37 antimicrobial peptide able to trigger the release of pro-inflammatory cytokines and sustaining proliferation [47]

While proteomics measures hundreds of proteins in clinical samples, the complex data processing and interpretation remain a significant challenge 8,9

Western Blotting SDS-PAGE Western blotting analysis was performed essentially as described in untov et al