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It's also worth noting that vitamin C acts as an enzymatic cofactor in the hydroxylation of proline and lysine, a crucial step in collagen synthesis

Researchers have spent decades looking for compounds that can slow or partially reverse these processes at the biological level

103 (11): 15971604n

When it comes to solubilizing Si, Bist et al

This process may involve its metabolite sphingosine-1-phosphate (S1P), indicating that modulating the production of sphingolipid metabolites could be a viable approach for restoring the phagocytic function of AMs to treat COPD (113)