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2018;11:dmm031906

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TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

However, molecular biology techniques of targeted mutations using CRISPR/Cas, as well as functional studies of protein production and characterization, with activity assays, in addition to in silico and in vitro studies of protein-ligand or protein-protein interactions, could clarify the specific roles of these motifs (Ltoff et al., 1998