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h , Bar graph showing relative fold change (log 2 ) in top 27 ER proteins of IP samples from ER-tag cells compared to those from control-tag HEK293T cells or to whole-cell lysate from ER-tag HEK293T cells

Moreover, given that drug exposure is expected to be highest in the olfactory bulbs compared to other brain regions, IN chelator therapy may be particularly beneficial for disorders involving early olfactory bulb pathology or localized iron dysregulation near the nasal region (Deng et al., 2024)