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Zinc: modulating inflammation, androgen production, and insulin resistance Zinc is an important trace mineral that is involved in many different physiological functions, including insulin production, oxidative stress responses, and regulating reproductive hormones

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This effect is achieved by promoting GDH1 expression through the downregulation of the epidermal growth factor receptor (EGFR)/MEK/ERK signaling pathway [56]

The mammalian target of rapamycin (mTOR), a key protein downstream of the phosphatidylinositol 3-kinase/protein kinase (PI3K/AKT) pathway, is closely associated with insulin metabolic dysfunction and exerts a substantial impact on the growth and proliferation of FGCs