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Whilst B12 plays a vital role in energy metabolism, supplementation does not promote fat loss in individuals with normal B12 levels

Mechanism of Action: How 5-Amino-1MQ Works The 5-amino-1MQ mechanism of action centers on its selective inhibition of the NNMT enzyme, creating a cascade of beneficial metabolic effects

It found that B12 deficiency was higher in vegans than vegetarians and that vegetarians report B12 deficiency irrespective of their demography, where they live, their age, and the type of vegetarian diet they eat

5-Amino-1MQ takes a very precise shot at the NNMT enzyme to protect NAD+ levels

National Academies Press (US).