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Long-Term Mortality in Elderly Khavinson et al., observational follow-up data Khavinson and colleagues conducted long-term observational follow-up of elderly patients receiving courses of pineal peptide preparations (including epithalamin and related compounds) and reported a 1.61.8-fold reduction in all-cause mortality over 23-year follow-up periods compared with untreated control groups

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We also confirmed the delayed formation of the thiomethyl metabolites compared to conventional APAP metabolites, likely related to delayed reabsorption into the systemic circulation after the enterohepatic circulation

Insulin-like growth factor-I enhances cell-based repair of articular cartilage

10.1038/tp.2016.188 Transl Psychiatry