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Description

The formation of pyridoxal and pyridoxal 5-phosphate hydrazones1

Decreased glomerular filtration, as well as the effects on tubular handling of uric acid of hydration, certain organic acids, drugs (in particular thiazide and loop diuretics) and exogenous toxins (e.g., lead), all impair renal excretion of uric acid ( Table 1 - 3 )