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A major drawback of nanoparticle use is the inclusion of heavy metals like lead, mercury, and tin, which are difficult to degrade due to their stable and rigid structure, posing environmental toxicity and health risks

In the cell, it triggers cellular modifications which change the arrangement of the whole cytoskeleton, and impair cellular motility, proliferation, and apoptosis

Methionine in the form of s-adenosyl methionine (SAMe) may have essential roles in hepatocyte metabolism 4

Bile duct injury Cholestatic and mixed liver injuries can damage the bile ducts, characterized by the destruction of the bile duct lining epithelium, potentially contributing to the progression of biliary cirrhosis