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The interaction between therapeutic antibodies and CD38 on neoplastic cells is inherently dependent on the availability of molecular targets

It is a natural form of vitamin B12 that is produced by certain microorganisms and occurs in the body

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Consistent with the findings from yeast in the current work, our previous characterizations of FL-associated V-ATPase mutants in human cells also found that when an FL-associated V-ATPase mutant is expressed, ATF4/Gcn4 is strongly induced 18 , suggesting that the V-ATPase-dependent autophagy pathway shares conserved regulatory mechanisms in eukaryotes