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As a potent, non-enzymatic antioxidant, it defends against environmental damage by blocking the enzyme that triggers melanin production to restore the skins surface and brighten complexions

Nonetheless, when a cell (e.g., a hepatocyte) is exposed to inflammation or oxidative stress, NRF-2 has the capacity to escape from regulation by KEAP1 through the increase in the transcription of mRNA from NRF-2, with the objective of depleting the reserves of KEAP1, which cannot be recycled because of the suppression of another NRF-2 [21]

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme

Journal of Biochemistry , 1972 (247), 31703175

4 Discussion In the present study we have analyzed the changes that occur in the intestinal microbiota with development to better characterize and distinguish the healthy microbiota of young children, adolescents, and adults