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For instance, doxorubicin and oxaliplatin induce eIF2 phosphorylation and oxidative stress, whereas paclitaxel or cisplatin frequently fail to elicit adequate ER stress or ROS, resulting in weak DAMP emission despite inducing tumor cell death

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Oral hypoglycemic agents are primarily used in the management of type 2 diabetes mellitus but often have other indications for use, including Polycystic Ovary Syndrome (PCOS) with irregular menstruation, prevention of ovarian hyperstimulation syndrome undergoing intracytoplasmic sperm injection (ICSI) with in vitro fertilization (IVF), or to reduce weight gain while on antipsychotic medication (10)

Certain genetic variations also affect enzyme production