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There is evidence that injury or stress in tissues leads to the exposure or release of Siglec ligands, which then engage receptors like Siglec-8 on infiltrating cells (181)

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However, we found that the ITIM of Ly49Q was important for actin remodeling in membrane regions where phagocytosis occurs

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Depressions multiple comorbidities explained by (neuro)inflammatory and oxidative & nitrosative stress pathways