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Because water is the solvent, these two p K a values have a different meaning than the values determined for typical solute acids

We propose that perinatal mast cell activation by environmental, infectious, neurohormonal and immune triggers could adversely affect neurodevelopment, disrupt the gut-bloodbrain barriers, and contribute to focal brain inflammation and ASD (Figure 1)

[40] Iwabuchi, T., Ideta, R., Ehama, R., Yamanishi, H., Iino, M., Nakazawa, Y., Kobayashi, T., Ohyama, M., & Kishimoto, J

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Your gut is home to trillions of microorganisms that help you digest food, produce vitamins, and support your immune system