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Adverse Reactions (Section 6.1, Clinical Trials Experience) Increases in pneumonia with concomitant clobazam : This added subsection reports clinical trial observations of increases in pneumonia in patients with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), and tuberous sclerosis complex (TSC) who were receiving Epildiolex with concomitant clobazam

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Based on Phase 2 trial protocols by Eli Lilly, initiation was typically at 2 mg once weekly via subcutaneous injection, with gradual dose escalation thereafter

Atorvastatin attenuates obese-induced kidney injury and impaired renal organic anion transporter 3 function through inhibition of oxidative stress and inflammation

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