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The main difference from proteins lies in their length and structure: peptides generally have molecular weights below 5000 Da and often lack stable three-dimensional structures, whilst proteins contain more than 100 amino acids, exceed 5000 Da in molecular weight, and fold into complex three-dimensional conformations with multiple functional domains

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Molecular dynamics analysis of NaOH aqueous solution surface and the sum frequency generation spectra: is surface OH - detected by SFG spectroscopy