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whereas, APX usually had 812 exons, implicating the relatively less conserved structure of APXs compared to GPXs

Studies have shown that compared with the general population, patients with COPD or impaired lung function face a higher risk of stroke and more significant cognitive decline [413,414,415,416]

ER stress inductionvia agents like Bortezomib or natural compounds such as Triptolidetriggers UPR activation and ROS-mediated cell death in malignancies with a high proteostatic burden