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DSIP is not included on WADA's prohibited list for athletes, unlike some other peptides

In TGR, and more generally in TrxRs, electron transfer from NADPH to the enzyme is fast and practically irreversible and so an actual ES complex (NADPH-TGR) is not significantly populated during the catalytic cycle 17

In HCM, where mitochondria sustain up to 5 higher ATP turnover to maintain hypercontractility, the CK shuttle is finally tested at its physiological limit

The peptide has a relatively short half-life of approximately 15 minutes, making timing important for optimal effectiveness

Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness