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Description

Myeloperoxidase Myeloperoxidase (MPO) is synthesized in neutrophils and monocytes and catalyzes the conversion of hydrogen peroxide to hypochlorous acid (HOCl) (Siraki 2021)

It helps neutralize free radicals and keep oxidative stress under control

Based on molecular docking analysis, computation toxicity studies, and the cheminformatics properties, we observe that the two metabolites desethylchloroquine and bisdesethylchloroquine have similar binding modes of action and drug-like properties albeit with significantly lower toxicity values compared to the parent CQ and HCQ molecules