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References Lee, Edwin, and Blake Padgett

Single-agent human RCTs remain sparse

The risks include unknown purity and concentration, potential contamination or mislabeling, no sterility guarantees, products manufactured overseas in facilities with zero oversight, and complete lack of accountability if something goes wrong

For example, ptsI mutants show very different phenotypes in BMDMs where no growth occurs compared to the L2 fibroblast plaquing assay where ptsI mutants are indistinguishable from wild type L

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