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doi: 10.1001/jama.2020.4006 96 BekkeringSArtsRJWNovakovicBKourtzelisIvan der HeijdenCLiYet al

It has been suggested that FOXO4-DRI protein or a variant of it may promote proteasomal functions, enhancing the function of cardiac tissues and reducing the risk of cardiovascular disease

Based on the above findings, we hypothesized that during neuroinflammation, elamipretide might protect against mitochondrial dysfunction, attenuate oxidative stress and the inflammatory response in the hippocampus, and thus improve memory impairment