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(4) The hydrolytic stability and reactivity of the PEG modifier depend on the stability of the activating group and the control of the modification reaction conditions, especially the pH

Appraisal of bioenhancers in improving oral bioavailability: applications to herbal medicinal products

The amino acid cysteine actively contributes to cancer metabolic remodelling on three different levels: first, in its free form, in redox control, as a component of the antioxidant glutathione or its involvement in protein s -cysteinylation, a reversible post-translational modification

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Emerging evidence also indicates an increased risk of HA in patients treated with VPA and carbonic anhydrase inhibitors (CAIs) such as topiramate (TPM) and acetazolamide (ACZ) [15,16,17]