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BCL3 , an IB family member, is known to inhibit TNF- -induced RelA phosphorylation and may suppress p53 Upregulated Modulator of Apoptosis (PUMA) expression via miR-34a upregulation 65,66

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Post-injection inflammation may present with directed severe pain, itching pain, redness, warmth, and induration, requiring treatment options such as oral analgesia, cold compresses, and avoiding immobilization of the affected limb