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Furthermore, recent high-throughput sequencing data demonstrate the significance of these dysregulated signaling pathways in sustaining supportive TMEs that facilitate the growth and metastasis of numerous solid tumors (Wang et al., 2023)

Under the stress of liver injury, bile duct cells undergo EMT and express fibroblast markers such as fibroblast-specific protein 1 (FSP-1), vimentin, and other mesenchymal markers in a diseased liver with ductular proliferation (90)

Several commenters urged CMS to refine its approach by incorporating improved risk adjustment and stratification and ensuring that modifications to the Overall Hospital Quality Star Rating methodology do not unfairly affect hospitals based on facility type, patient acuity, or mission

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8 Surgical Treatment Surgical management of PD is indicated for patients with a deformity that impairs sexual function, such as severe penile curvature, penile instability due to an hourglass deformity, or other narrowing deformities