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Intracellular iron overload not only inhibits osteoblast function but also enhances osteoclast activity, thereby contributing to osteoporosis

Nevertheless, SASP can increase mortality in mice and also cause adverse effects such as weight loss and hypothermia, regardless of the impact of intact SASP or its metabolites on the system (89)

Glutathione S-transferase mu in human lymphocyte and liver: role in modulating formation of carcinogen-derived DNA adducts

Ubiquitin-specific protease 24 (USP24) promotes ferroptosis by activating NF-B pathway, upregulating ACSL4 levels, and reducing SLC7A11 and FTH1 levels, thereby decreasing the antioxidant capacity of cardiomyocytes

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