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Bioengineered 4 17 10.4161/bioe.26003 [DOI] [PMC free article] [PubMed] [Google Scholar] Davis G

More concerning are findings from systematic reviews and meta-analyses indicating dose-dependent hepatotoxicity and an increased risk of clinically significant liver enzyme elevations, especially when CBD is taken with drugs like valproate that share metabolic pathways

Nelson HK, Shi Q, Van Dael P, et al

Similarly, charge density and headgroup structure influence membrane rigidity [7], create variation in protein-lipid interactions and liposome membrane mobility [8], and determine the ability of lipid-DNA complexes to transfect DNA in vitro [9]