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Food and Drug Administration (FDA) in 1990 and 1997, respectively, for the treatment of idiopathic growth hormone deficiency (GHD) in children with growth failure, or for evaluating the ability of the growth hormone producing cells, called somatotrophs, of the pituitary gland to secrete growth hormone

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Procedure: Remove the desired strips from the aluminum foil bag after equilibration at room temperature for 10 minutes

In a double-blind, randomized study, subjects administered 3 g of L-Arg three times a day for 6 months exhibited increased coronary blood flow in response to increased acetylcholine, which was explained by a decrease in the levels of plasma endothelin in the L-Arg-treated group compared with the placebo group (150)

Loftus et al, 1997)