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Selenoproteins influence the integrity of the intestinal barrier, and their reduced expression promotes increased intestinal permeability and bacterial translocation [57], which is essential in the development of inflammatory bowel diseases, metabolic disorders, and autoimmune diseases

In addition to hormonal signaling, emerging small molecules enhance antioxidant transcription

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With the capacity to freely cross the placenta, exogenous ketone treatment has been reported to preserve cerebral energy metabolism, ameliorate brain damage, and display effective neuroprotective potency during neonatal hypoxia-ischemia (24, 25)

The pellet was washed three times with 1X PBS pH 7.4, following which cells were resuspended in 35 mL of 1X PBS for the assay