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Description

Burnett JR, Hooper AJ, Hegele RA

approval in 2002, contains an interesting nuance most summaries leave out

A stock of 1 mM of xanthine was prepared in 50 mM Tris, pH 8.0, and stored at room temperature

HT-29 cells were treated first with 20 M Z-VAD-FMK for 30 min and then treated with an addition of 10 M Smac mimetic LCL-161 and 20 ng/mL human TNF for 24 h to induce necroptosis