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The SP@M recovers the balance of synovial microenvironment, and finally achieves bone remodeling and cartilage restoration in collagen-induced arthritis (CIA) mouse models (Fig

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These findings indicate that selection of AC5 versus AC6 by GsPCRs determines cAMP localization which controls cAMP fate, thus altering cardiomyocyte survival (Zhang et al., 2023)

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