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Heterogeneous pathology of melasma and its clinical implications

Retinol works through the retinoid receptor pathway (RAR/RXR), directly upregulating specific procollagen genes and inhibiting matrix metalloproteinases (MMPs) that break down existing collagen [6]

1 , 2 , 3 Throughout the rest of the 20 th century, tanning products saw some use but were plagued by poor product performance such as undesirable color tones and streakiness

347,348 Studies have demonstrated that this method enhances the efficacy of chemotherapeutic agents such as etoposide, paclitaxel (PTX), and DOX, reducing tumor growth and extending survival

14(17) 1669-1678) report the results of a phase III study with the ADC mirvetuximab soravtansine, comprising mirvetuximab, a humanized anti- FRa antibody, conjugated with an average of 3 to 4 maytansinoid molecules as the payload, for the treatment of ovarian cancer