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Description

Carnitine, thus, acts as a shuttle, ferrying fatty acids to the mitochondrial furnace, where they are oxidized to produce adenosine triphosphate (ATP), the body's primary energy currency

10.1007/s12035-023-03782-1 Mol

For example, patients with systemic primary carnitine deficiency (SPCD) have a deficiency in carnitine due to a mutation in the plasma membrane sodium-dependent high affinity carnitine transporter (OCTN2) that enables cellular carnitine uptake in the heart, muscle, and kidney