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Hrd1 can recognize and bind NRF2, directing it to the ERAD pathway for ubiquitination and proteasomal degradation [55]

Lactic acid is similarly gentle and has the added benefit of being a natural moisturizing factor, which keeps the barrier from becoming excessively dry during treatment

In addition, the use of cell lines or mouse models has facilitated the investigation of gene expression and diet-induced beta cell dysfunction (150, 151)

Through co-culture experiments with glial cells and neurons, it was found that glial cells can help neurons resist oxidative stress by secreting antioxidants or helping antioxidant precursors

402 Indeed, the reduction in zinc levels in pancreatic intraepithelial neoplasia (PanIN) lesions and malignancy is attributed to the downregulation of Ras responsive element binding protein 1 (RREB-1) and the silencing of ZIP3