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J Clin Endocrinol Metab

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In this article, we review efforts to develop new drugs targeting these processes, including agents that reactivate fetal haemoglobin, anti-sickling agents, anti-adhesion agents, modulators of ischaemiareperfusion and oxidative stress, agents that counteract free haemoglobin and haem, anti-inflammatory agents, anti-thrombotic agents and anti-platelet agents

In diabetes, reduced GPx in kidneys exacerbates nephropathy, with oxidative damage fueling complications

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

The clinical efficacy of glutathione is also supported by large-scale patient-reported outcomes among people managing the overlapping triad of Long COVID, ME/CFS, and POTS/dysautonomia, where glutathione therapies are frequently rated among the more helpful interventions for this complex neuroimmune symptom cluster